Cholera vaccine

DUKORAL®

Cholera vaccine (inactivated, oral) 
DUKORAL® is the only licensed and recommended cholera vaccine in the UK1. Help protect your travellers against cholera.

DUKORAL

Key facts

  • Licensed for adults and children from 2 years of age to help protect against cholera2
  • Contains inactivated Vibrio cholera O1 bacteria and the recombinant non-toxic B-subunit of the cholera toxin (CTB)2
  • Has demonstrated 84% – 86% protection against cholera, across 3 continents3-5
  • A drinkable formulation which is convenient and easy to take2
  • No special requirements concerning the water Dukoral is made with,either cool or chlorinated water can be used
  • A booster should be given within 2 years for adults and children over 6 years of age and within 6 months for children aged 2 – 6 years of age2
  • It is not contraindicated with any malaria prophylaxis
  • Established vaccine with a proven safety profile

How you should administer DUKORAL®

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View Product InformationFurther information on SMPC Further information on PIL

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References

  1. Public Health England. Immunisation against infectious disease. Cholera: the green book, chapter 14. December 2013. Available online. (Last accessed April 2018).
  2. Valneva UK Limited. DUKORAL® Summary of Product Characteristics. December 2015. Available online. (Last accessed April 2018).
  3. Clemens JD, Sack DA, Harris JR et al. Field trial of oral cholera vaccines in Bangladesh. Lancet 1986;2:124–127.
  4. Sanchez JL, Vasquez B, Begue RE et al. Protective efficacy of oral whole-cell/recombinant-B- subunit cholera vaccine in Peruvian military recruits. Lancet 1994;344:1273–1276.
  5. Lucas M, Deen JL, von Seidlein L et al. Effectiveness of mass oral cholera vaccination in Beira, Mozambique. N Engl J Med 2005; 352: 757–767.

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